Friday, March 20, 2020
Rice Production Essays
Rice Production Essays Rice Production Essay Rice Production Essay I. Introduction The most important food crop in the Philippines is rice, a staple food in most of the country. It is produced all throughout Luzon, the Western Visayas, Southern Mindanao, and Central Mindanao. 9. 5 billion tons of palay were produced in 1989 almost. In 1990 palay, which caused a 27 percent value added in agriculture and 3. 5 percent of GNP. Per hectare yields have generally been low in comparison with other Asian countries. Since the mid-1960s, however, yields have increased substantially as a result of the cultivation of high-yielding varieties developed in the mid-1960s at the International Rice Research Institute located in the Philippines. The proportion of miracle rice in total output rose from zero in 1965-66 to 81 percent in 1981-82. Average productivity increased to 2. 3 tons per hectare (2. 8 tons on irrigated farms) by 1983. By the late 1970s, the country had changed from a net importer to a net exporter of rice, albeit on a small scale. In the 1980s, however, rice production encountered problems. Average annual growth for 1980-85 declined to a mere 0. 9 percent, as contrasted with 4. 6 percent for the preceding fifteen years. Growth of value added in the rice industry also fell in the 1980s. Tropical storms and droughts, the general economic downturn of the 1980s, and the 1983-85 economic crisis all contributed to this decline. Crop loans dried up, prices of agricultural inputs increased, and palay prices declined. Fertilizer and plant nutrient consumption dropped 15 percent. Farmers were squeezed by rising debts and declining income. Hectarage devoted to rice production, level during the latter half of the 1970s, fell an average of 2. 4 percent per annum during the first half of the 1980s, with the decline primarily in marginal, nonirrigated farms. As a result, in 1985, the last full year of the Marcos regime, the country imported 538,000 tons of rice. The situation improved somewhat in the late 1980s, and smaller amounts of rice were imported. However, in 1990 the country experienced a severe drought. Output fell by 1. 5 percent, forcing the importation of an estimated 400,000 tons of rice. In few years, we may have to squeeze out whatever is left of the countryââ¬â¢s rice stock. This paper aims to find out what factors affect the production of rice in the Philippines to be able to formulate policies which may give the Filipinos more than enough hope and promise to help Filipinos on the way not only to rice sustainability, but also to national food security. II. Statement of the problem and object of the analysis General: This paper attempts to analyze Palay Production in the Philippines from the first semester of 1991 to the second semester of 2002 as affected by the size of land used for planting palay, amount of rain, and advancement of technology. Specific: More specification, this paper answers the following questions: 1. Does each of the following variables has significant effect on Palay Production. a. Area of land allotted for planting palay. b. Amount of rainfall. c. Advancement of technology. 2. Is there a significant effect on rice production given that the area of land allotted for planting palay, amount of rainfall, and advancement of technology are combined. III. Specification of the model This paper utilized a multiple linear regression model which can be described as follows: PROD = b0 + b1AREA + b2RAIN + b3TECH Where: b = parameters estimates PROD = volume of rice produced AREA = area of land allotted for planting palay RAIN = amount of rainfall in the areas TECH = advancement of technology in the agricultural sector Furthermore, to determine the individual level of significance of every ndependent variable, the t-statistic will be used. In order to estimate the values of coefficient, the Least Square Method was used, with a confidence level of 95 percent, while to probe into to over-all significance to these variables to the dependent one, the f-statistic was used. Finally, the results are to be validated through the usage of R2 which determines the degree of influen ce of all variables to the dependent component. The level of significance used in this study is 5 percent, while the degrees of freedom is 21, derived by deducting the number of observations (24) by the number of independent variables in consideration (3). IV. Hypothesis To Be Tested That the variables such as area allotted for planting palay, amount of rainfall, advancement of technology in the agricultural sector have no significant effect on rice production in the Philippines. V. Presentation of Data The Table below shows the data from the first semester of 1991 to the second semester of 2002, showing figures about palay production, area harvested, amount of rainfall and the advancement of technology. Palay ProductionArea HarvestedRainfallTechnology (All Ecosystem, In Metric Tons)(All Ecosystem, In Hectares)(in millimeters)Trend variable PRODAREARAINTECH 1991. 1 4,047,513 1,418,640 6,674. 0 1 1991. 2 5,625,749 2,006,320 13,124. 0 2 1992. 1 3,505,984 1,282,330 6,623. 7 3 1992. 2 5,622,956 1,915,740 16,278. 0 4 1993. 1 3,890,149 1,320,700 6,319. 8 5 1993. 2 5,544,059 1,961,650 18,756. 5 6 1994. 1 4,378,533 1,483,330 10,362. 5 7 1994. 2 6,159,521 2,168,200 13,995. 8 1995. 1 4,317,331 1,501,408 7,510. 3 9 1995. 2 6,223,318 2,257,283 21,217. 0 10 1996. 1 4,950,910 1,666,483 10,704. 3 11 1996. 2 6,332,658 2,284,653 16,258. 0 12 1997. 1 4,846,461 1,624,241 7,303. 0 13 1997. 2 6,422,502 2,218,029 11,052. 9 14 1998. 1 3,558,976 1,283,197 4,974. 4 15 1998. 2 4,995,848 1,886,845 24,330. 5 16 1999. 5,272,053 1,743,026 19,011. 6 17 1999. 2 6,514,572 2,256,813 26,291. 3 18 2000. 1 5,442,496 1,737,623 17,458. 1 19 2000. 2 6,946,916 2,300,462 27,202. 0 20 2001. 1 5,567,831 1,729,096 13,767. 5 21 2001. 2 7,387,039 2,336,345 23,721. 0 22 2002. 1 5,672,369 1,753,200 10,637. 3 23 2002. 2 7,598,284 2,293,118 20,401. 0 24 Prod = f(area, r ain, tech) VI. Summary of Findings After processing the gathered data into information, through the regression analysis, AREA, RAIN, TECH, and PROD, gave off the following estimated regression equation and other regression results: PROD = -282911 + 2. 959577AREA ââ¬â 14. 77746RAIN + 37848. 18TECH The equation states that at every 1hectar increase in Area, there would be a 2. 959577 metric ton increase in rice production. Ceteris paribus. It also shows a negative relation between rainfall and rice production, were an increase of 1mm. Of rain fall would cause a decrease of 14. 7746hectars of rice, ceteris paribus. Finally, the equation also indicates a positive relation between technological advancements to rice production. As technology has a 1 unit increase, rice production would increase by 37848. 18. Dependent Variable: PROD Method: Least Squares Date: 07/12/04 Time: 23:04 Sample: 1991:1 2002:2 Included observations: 24 VariableCoefficientStd. Errort-StatisticProb. C-282911. 0334520. 1-0. 845 7220. 4077 AREA2. 9595770. 24752211. 956820. 0000 RAIN-14. 7774613. 73005-1. 0762860. 2946 TECH37848. 188842. 3054. 2803520. 0004 R-squared0. 954369 Mean dependent var5451001. Adjusted R-squared0. 947524 S. D. dependent var1137085. S. E. of regression260478. 8 Akaike info criterion27. 92944 Sum squared resid1. 36E+12 Schwarz criterion28. 12578 Log likelihood-331. 1533 F-statistic139. 4325 Durbin-Watson stat1. 048045 Prob(F-statistic)0. 000000 The regressed data show that only the amount of rainfall has no significant effect on the dependent variable, as shown by the variablesââ¬â¢ t-statistic. It did not meet the critical value of 2. 080 with a t-statistic of 1. 76286. All in all, the whole estimated equation is highly significant as shown by the f-statistic of 0. 0000. There is a 0. 954369 R-squared data, which shows that there is a 95. 44% influence of independent variables to the dependent variable. This graph shows the trend of Rice Production in the Philippines and amount of Rainfall during 1991 to 2002. As one can observe, rice production and rainfall are almost going at the same trend, but when there was a massive amount of rainfall during 1998, rice production slowed itââ¬â¢s ascend to itââ¬â¢s peak. This graph shows the trend of rice production and area for planting palay from the first semester of 1991 to the second semester of 2002. as we can observe, the graphs are almost overlapping each other, except during 1998, where rice production slowed during the beginning of the second semester. VII. Conclusion With the countryââ¬â¢s fast increase in population and the slow pace of our technology and limited land area, the rice our farmers are producing are not sufficient to feed all of our ââ¬Å"kababayansâ⬠and have more to sell throughout the world. Policy makers should try to formulate policies that would help increase rice production. The input requirements of the new technologies were skewed, in the direction of capital inputs, mainly irrigated land, fertilizers and other forms of capital. By definition, capital is scarce, and therefore the implementation of the new technologies stretched over a long period of time. This is on the supply side, whereas on the demand side, the countries have to expand their export in order to supplement the growing domestic demand in absorbing the growing supply. The message for the future is clear, for the growth to continue, the available technologies must continue to grow. Without such growth, the impact of input growth will eventually decline; we see some evidence to this effect already in the estimated regression equation. But this is not the only determinant of future growth. In order to take a full advantage of new techniques, there must be a smooth flow of the required resources into agriculture. VIII. Bibliography Economic Development 8th edition, by Michael s. Todaro and Stephen C. Smith, page 418-454 Agricultural Statistics c/o San Beda College Prof. Harold Glenn Valera
Wednesday, March 4, 2020
25+ TERRIFIC Repetition Examples in Literature
25+ TERRIFIC Repetition Examples in Literature 25+ TERRIFIC Repetition Examples in Literature Editing 101 will always tell you the same thing: avoid repetition in your writing. But make no mistake, repetition isnââ¬â¢t a pariah in à the world of prose! In fact, when executed with finesse, it can make a piece of writing all the more compelling.This post will take you through the basics of repetition. And because the best way to understand a literary device is to see it in skilled action, weââ¬â¢ll also cover 30 remarkable examples of repetition in literature. (To skip past the next section where we define repetition, you can jump straight to those examples!)Repetition definitionRepetition is the act of repeating sounds, words, phrases, or full sentences. As a literary device, itââ¬â¢s used to stress key points, or to achieve a certain rhythm, tone, or style of prose - which is why youââ¬â¢ll often find it in poetry.However, while it can be used to highlight important details or enhance rhythm, repetition needs to be done with care. If you accidentally repeat wor ds or re-state the same information for readers over and over (and over) again, it can become jarring. For instance, if youââ¬â¢ve already told readers that a character has an unusual beauty mark on their shoulder, mention it once and leave it at that. Hearing about the beauty mark every time that character is in a scene is tiring. If itââ¬â¢s crucial to bring it up more than once, find new and interesting ways of bringing attention to it - instead of just stating its existence, maybe you can have another character comment on it.If youââ¬â¢re going to repeat a word, phrase, or idea, it needs to have a purpose. Pinpoint exactly why it needs to be said again - or if thereââ¬â¢s another way you present it that adds more to the narrative.To à figure out the right way to use this literary device, you first have to learn the different types of repetition. Learn more about how Reedsy can help you craft a beautiful book.Types of repetitionDid you know that there are at least 15 main types of repetition? They fall into two categories: words and sounds. Letââ¬â¢s start with...Repetition of Words1. Anadiplosis The last word of a clause or sentence is repeated as the first word of the next one.Example: "Fear leads to anger; anger leads to hatred; hatred leads to conflict; conflict leads to suffering." - Yoda, in Star Wars Episode I: The Phantom Menace.2. Anaphora The word or phrase at the beginning of successive clauses or sentences is repeated.Example: ââ¬Å"It rained on his lousy tombstone, and it rained on the grass on his stomach. It rained all over the place.â⬠- The Catcher in the Rye by JD Salinger3. Antistasis The repetition of words or phrases in different or contrary senses.Example: ââ¬Å"We must, indeed, all hang together or, most assuredly, we shall all hang separately.â⬠à - Benjamin Franklin4. Conduplicatio The frequent repetition of a word or phrase within a paragraph, in order to expand upon its meaning.Example: ââ¬Å"Now is the time to make real the promises of democracy. Now is the time to rise from the dark and desolate valley of segregation to the sunlit path of racial justice. Now is the time to lift our nation from the quicksands of racial injustice to the solid rock of brotherhood. Now is the time to make justice a reality for all of God's children." - Martin Luther King, Jr.5. Diacope The repetition of words separated be additional words, which alter their meaning.Example: ââ¬Å"We few, we happy few, we band of brothers.â⬠- Henry V by Shakespeare6. Epanalepsis The word both at the beginning and at the end of the clause or sentence is repeated.Example: ââ¬Å"Next time there won't be a next time.â⬠- Phil Leotardo, in The Sopranos7. Epimone The word or phrase is repeated to place emphasis on its meaning.Example: ââ¬Å"Mr. Dick shook his head, as utterly renouncing the suggestion; and having replied a great many times, and with great confidence, ââ¬ËNo beggar, no beggar, no beggar, Sir!ââ¬â¢Ã¢â¬ - David Copperfield by Charles Dickens (Are you a Dickens fan? Read up on 15 of his classics novels in our guide to Dickens!)8. Epiphora The repetition of a word or phrase at the end of a series of clauses or sentences.Example: If you did know to whom I gave the ring, If you did know for whom I gave the ring And would conceive for what I gave the ring And how unwillingly I left the ring, When naught would be accepted but the ring, You would abate the strength of your displeasure. - The Merchant of Venice by Shakespeare9. Epizeuxis The successive repetition of a word or phrase within one clause or sentence.Example: ââ¬Å"The horror, the horror.â⬠- Heart of Darkness by Joseph Conrad10. Negative-Positive Restatement An idea or phrase is presented in negative terms, and then repeated in positive terms.Example: ââ¬Å"The tragedy of old age is not that one is old, but that one is young.â⬠- The Picture of Dorian Gray by Oscar Wilde11. Polyptoton The same root word is repeated in different forms.Example: ââ¬Å"Today you are You, that is truer than true. There is no one alive who is Youer than You.â⬠- Happy Birthday to You! by Dr. Seuss12. Symploce The repetition of a word or phrase both at the end and at the beginning of a clause or sentence. (In other words, a combination of à anaphora and epiphora.)Example: "The yellow fog that rubs its back upon the window-panes, The yellow smoke that rubs its muzzle on the window-panesâ⬠¦Ã¢â¬ - ââ¬Å"The Love Song of J. Alfred Prufrockâ⬠byà T.S. EliotSound RepetitionDo you hear that? Is it bat, a rat, or a gnat? And speaking of sounds that repeat themselves, letââ¬â¢s take a look at...13. Alliteration The successive repetition of consonant sounds in the stressed part of a word.Example: ââ¬Å"She sells seashells by the sea-shore.â⬠14. Assonance The vowel sounds are repeated.Example: ââ¬Å""Hear the mellow wedding bellsâ⬠¦Ã¢â¬ - ââ¬Å"The Bellsâ⬠byà Edgar Allan Poe15. Consonance The repetition of consonant sounds in successive or closely connected words. The difference between consonance and alliteration is that alliteration is at the beginning of the word (so ââ¬Å"Peter Piperâ⬠), but consonance can be anywhere in the word.Example: I'll swing by my ankles. She'll cling to your knees. As you hang by your nose, From a high-up trapeze. But just one thing, please, As we float through the breeze, Don't sneeze. - ââ¬Å"The Acrobatsâ⬠by Shel SilversteinOkay, now that weââ¬â¢ve gotten seamlessly up to speed (pardon the alliteration), on the different types of repetition, letââ¬â¢s look at some exemplary examples from literature (pardon the polyptoton).Repetition examples in literatureLetââ¬â¢s turn this section into a little quiz. Try to guess what kind of repetition each quote is using as you read through - the answers will be provided at the bottom!Example #1:à The Hitchhiker's Guide to the Galaxy byà Douglas Adams"Space is big. You just won't believe how vastly, hugely, mind-bogglingly big it is. I mean, you may think it's a long way down the road to the chemist's, but that's just peanuts to space."Example #2:à The Innocents Abroad byà Mark Twain"They are not paid for thinkingthey are not paid to fret about the world's concerns. They were not respectable peoplethey were not worthy peoplethey were not learned and wise and brilliant peoplebut in their breasts, all their stupid lives long, resteth a peace that passeth understanding!"Example #3: Deep River byà Shusaku Endoââ¬Å"Hatred was spreading everywhere, blood was being spilled everywhere, wars were breaking out everywhere.â⬠Example #4:à A Tale of Two Cities byà Charles Dickensââ¬Å"It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, it was the season of Light, it was the season of Darkness, it was the spring of hope, it was the winter of despair, we had everything before us, we had nothing before us, we were all going direct to Heaven, we were all going direct the other way- in short, the period was so far like the present period, that some of its noisiest authorities insisted on its being received, for good or for evil, in the superlative degree of comparison only.â⬠Example #5:à Beloved byà Toni Morrisonââ¬Å"Beloved is mine; she is B eloved.â⬠Example #6:à Lolita by Vladimir Nabokovââ¬Å"What I present here is what I remember of the letter, and what I remember of the letter I remember verbatim (including that awful French).â⬠Example #7:à Outer Dark by Cormac McCarthyââ¬Å"And stepping softly with her air of blooded ruin about the glade in a frail agony of grace she trailed her rags through dust and ashesâ⬠¦Ã¢â¬ Answers:à a) Epimone; b) Symploce; c) Epistrophe; d) Anaphora; e) Epanalepsis; f) Anadiplosis; g) AssonanceExamples of repetition in poetryRepetition is especially prevalent in poetry, as it can help achieve a certain resonance with readers. Again, read through the following examples of poetic repetition and guess what type each uses.Example #1: "Stopping by Woods On a Snowy Evening" by Robert Frostââ¬Å"The woods are lovely, dark, and deep, But I have promises to keep, And miles to go before I sleep, And miles to go before I sleep.â⬠Example #2: "Do Not Go Gentle into the Good Night" by Dylan Thomasââ¬Å"Do not go gentle into that good night, Old age should burn and rave at close of day; Rage, rage, against the dying of the light. Grave men, near death, who see with blinding sight, Blind eyes could blaze like meteors and be gay, Rage, rage against the dying of the light.â⬠Example #3: ââ¬Å"Annabel Leeâ⬠by Edgar Allen Poeââ¬Å"It was many and many a year ago, In a kingdom by the sea, That a maiden there lived whom you may know By the name of Annabel Lee; And this maiden she lived with no other thought Than to love and be loved by me.â⬠Example #4: "Song of Myself, 3" by Walt Whitmanââ¬Å"There was never any more inception than there is now, Nor any more youth or age than there is now, And will never be any more perfection than there is now, Nor any more heaven or hell than there is now.â⬠Example #5: "A Child is Born" by Stephen Vincent Benetââ¬Å"Life is not lost by dying! Life is lost Minute by minute, day by dragging day, In all the thousand, small uncaring ways.â⬠Example #6: "The Gnome, The Gnat, The Gnu" by Shel Silverstein"I saw an ol' gnome Take a gknock at a gnat Who was gnibbling the gnose of his gnu. I said, "Gnasty gnome, Gnow, stop doing that."Example #7: "Coda" by Dorothy Parkerââ¬Å"Thereââ¬â¢s little in taking or giving, Thereââ¬â¢s little in water or wine; This living, this living, this living Was never a project of mine.â⬠Answers: a) Epizeuxis; b) Assonance; c) Consonance; d) Epiphora; e) Diacope; f) Alliteration ; g) Epizeuxis Did you know there are over 15 types of repetition? Now that you know how to make repetition your writingââ¬â¢s best friend, letââ¬â¢s give a shout-out to your best friend when it comes to removing unnecessary repetition: CTRL+F. We are all guilty of over relying on specific words that crop up in our writing again and again. Get acquainted with your own habitual words, and then use CTRL+F to sweep your document for them. Find, remove, repeat! ðŸËÅ Do you incorporate repetition into your prose? Is there a specific type that you favor? Leave any thoughts or questions in the comments below!
Sunday, February 16, 2020
Project Management Systems Research Paper Example | Topics and Well Written Essays - 1500 words
Project Management Systems - Research Paper Example A project manager is a person who is responsible for carrying out all the tasks and operations that are included in project management. In simple words, both the success and failure of a project centralizes on the project managerââ¬â¢s shoulders (Haughey, 2009; Grembergen, 2002, p. 89; Hallows, 1998, p. 4). This paper presents a detailed analysis of roles and responsibilities that a project manager carries out. The purpose of this research is to analyze the impact of project managerââ¬â¢s performance on a project. This paper will also outline some examples of bad project management. Project management is a systematic way to scheduling and managing project activities and resources from beginning to end. Additionally, these project activities are divided into five phases, first phase is the initiation, the second is planning, the third phase is executing, fourth is controlling, and last phase is the completion or termination of the project. In addition, these phases of project management can be used in approximately any kind of project, since their purpose is to organize the different processes of project development. The fundamental reason for starting a project is to achieve particular objectives. In other words, the purpose of managing the processes as a project is to put attention on the jobs and control for the accomplishment of the objectives on small group or an individual. Additionally, a project is normally a temporary endeavor encompassing a lot of interconnected operations or processes, assigned a considerable cost, and continuing for a few weeks or, m onths, or years. However, the management of a project is a complex and challenging task and the roles of project managers vary with the project requirements (TechTarget, 2008; Meredith & Mantel, 2006, p. 13; Turban, Leidner, McLean, & Wetherbe, 2005, p. 309). The
Monday, February 3, 2020
Disadvantages of herbal remedies Speech or Presentation
Disadvantages of herbal remedies - Speech or Presentation Example The government does not support any institutions as such that help prepare these herbal remedies so there is no quality control and the user may end up buying a low quality treatment. Also, herbal remedies do not work in serious illnesses and injuries. Herbs cannot replace surgeries, laboratory tests, and operations. Sometimes, herbal treatment negatively interacts with the formal medicines like anti-depressants and thus may hinder with their effect. Since, herbal remedies do not come with an instruction manual or package insert, so this becomes very likely that the user will overdose the remedy. Also, some herbs get poisonous when they are harvested in wild, or some part of the plant gets venomous, so when these are extracted into a remedy, the user will also catch that poison. In short, the use of herbal remedies depends mainly on the user himself because he should know what kind of herb he is using, what he is using it for, and for how long he has to use it.
Saturday, January 25, 2020
Hepatitis E Virus Infection in HIV-Infected Persons
Hepatitis E Virus Infection in HIV-Infected Persons Hepatitis E virus (HEV) infection is a global disease (1,2). HEV infection represents a major global public health issue especially in developing countries, where the global death rate is 1-15% and up to 30% in pregnant women (3). Every year there are an estimated 20 million hepatitis E infection (HEV) are registered over the world. it is known that chronic liver disease by hepatitis E develops in persons who are undergoing immunosuppression, including individuals infected with HIV(4). Recently, many studies have demonstrated cases of chronic HEV infection (characterized by detection of HEV RNA greater than or equal to 6 months in plasma) and cirrhosis in immunocompromised patients, including organ transplant recipients(5) patients with lymphoma and haematological malignancies (4,6 ) and in persons infected with the human immunodeficiency virus (HIV) (7). A number of studies have suggested that In persons infected with HIV may acquire HEV infection more often than individuals without HIV (8,9). The first verified case of chronic infection E in 2008 (10), which can to lead to liver damage and develops of hepatic fibrosis and even cirrhosis in immunosuppressed patients such as Patients with human immunodeficiency virus (HIV) infection and solid organ transplant recipients (11-14). Immunosuppression has been shown that facilitates chronicity of HEV infection, Therefore HIV infection is one of the possible causes for HEV persistence (15) and there are published reports of high HIV/HEV co-infection rates for particular regions (16,17). There are some data that suggest that HEV may promote the progression of liver disease due to other causes (18). There are only a few reports regarding HEV seroprevalence in Individuals who are immunocompromised. The seroprevalence of anti- HEV IgG in HIV-positive cohorts ranges varies from one geographic location to another from 1.5% to 11.2% (19,20). Incidence of infections caused by HEV, defined by detecting HEV RNA in the serum, i s low, ranging from 0 to 1.3% (21-23). However, studies regarding co-infection of HIV and HEV and HEV associated chronic liver disease in HIV-infected patients are limited in IRAN. The present study aimed to determine the prevalence of HEV RNA in HIV infected patients in Iran a country with moderately high prevalence of both infections. Therefore, in order to better understand the clinical impact of HEV infection in these populations we have conducted a study determining HEV RNA in HIV-infected patients. In the present study, we determined whether HEV RNA were present in serum samples obtained from HIV-infected patients to investigate the prevalence of, and factors associated with, HEV infection in HIV-infected individuals. In addition, epidemiological, clinical and analytical factors were analyzed in order to identify potential risk factors associated with HEV seropositivity. The aim of this study was to define the degree of prevalence of HEV RNA in the group of HIV infected patients in Iran. For this study real-time RT-PCR assays targeting ..genes have been developed. We report 6 cases of hepatitis E infection in HIV-infected patients thatà none of our patients received ribavirin treatment. Methods and materials: à à Study population and samplecollection: A total of 80 Iranian patients with HIV-1 infection attending the Tehrans hospitals were enrolled in this study from February 2015 to April 2016. The exclusion criteria considered as patients who had been received anti-retroviral therapy. This study followed the principles of the Declaration of Helsinki and study has been approved by a local research ethics committee of the Iran University of Medical Sciences, Tehran, Iran. The participants were informed all aspects of the current study, and Informed consent was obtained from all of the participants prior to their enrollment for current study. About 5 ml of peripheral whole blood Sample from each participant was collected into a sterile EDTA-containing Vacutainer tube and plasma was separated from blood via centrifugation and frozen at -70 oC until analysis. HEV RNA Extraction: Efficient HEV RNA extraction using the High Pure Viral Nucleic Acid Kit generates purified HEV RNA was extracted from 200 ml of plasma (Roche Diagnostics, Germany). RNA pellets eluted with the provided elution buffer and stored at -70à °C until analysis. cDNA Synthesis: For detection HEV RNA, Reverse transcription polymerase chain reaction (rReal Time PCR) was was performed by using the first strand cDNA synthesis kit by Revert AidcDNA synthesis kit from RNA templates (Thermoscientific, USA). In a nutshell, RNA samples were heated in 65à °C for 10 minutes, then chilled on ice. The uniform suspension of bulk first-strand cDNA reaction mix was added according to the manufacturers protocol, then One à ¼l of DTT solution, and 1 à ¼l of random hexamer (24) primer (0.2 à ¼g) were added to the RNA After heat denaturation and RNA and RT primers were mixed properly by pipetting up and down for several times, then incubated for an hour at 42à °C. For Real time PCR, the QuantiTect Probe PCR Kit (Qiagen, Germany) was used, based on its instruction kit. HIV-1 viral load quantification: Measurement of blood plasma HIV-1 RNA concentration performed by COBAS TaqMan 48 (Roche Diagnostics, Hacienda Drive Pleasanton, CA, USA) kit in the patients plasma samples (500 à ¼l) and high pure extraction was used according to the manufactures recommendation. This method is a Real-Time PCR based on dual-labeled hybridization probe which targets the highly conserved region of HIV-1 gag gene. Limit of Detection of the COBAS TaqMan HIV-1 Test is 48 to 107 copies/mL. Hepatitis E Virus real time PCR assay: A Real Time PCR assay was developed for detection of HEV RNA. The primers amplify a bp region containing the . variable regions of the .. Primers sequences and their position with melting temperature are shown in . So, after alignment of complete genomes, HEV consist of Nucleotide sequences based on pubmed database. Reactions contained 5à µl of cDNA, 2.5 mmol/L MgCl2, 800 mmol/L of dNTPs, 100 ng of each primer,30 ng of probe and 1.5 units of QuantiTect Probe PCR Kit (Qiagen, Germany) to a total volume of 15 à µL. Thermal cycling conditions were as follows: 95à °C for 10 min; 40 cycles of 95à °C for 15 sec, 60à °C for 40 sec, Quantitative determination of the amplified products have done by the BioRad CFX-96 instrument (BioRad, USA). In order to synthesis our ideal genes, tests should be done by two pairs of forward and reveres primers. Our specific probes were designed by different fluorescent labels to track our targets separately. Statistical analysis:The statistical analysis was performed using the Statistical Package for Social Sciences software version 21 (SPSS Inc, Chicago, IL, USA). Categorical variables were compared by Fishers exact test or the chi-square test as appropriate. Continuous variables was analyzed using Students t test. Data are presented as absolute counts, proportions [95% binomial exact confidence intervals (CI)], medians [interquartile range (IQR)], and means [standard deviation (SD)]. For all comparisons, p-value less than 0.05 was considered statistically significant. Results: The study population consisted of 80 participants with HIV-1 infection that were enrolled in the current study . The mean age of the patients was 36.51 à ± 12.75 (range 4-64) years. Among 150 participants, 95 (63.3 %) were male and 53 (35.3 %) were female. . Real-Time PCR assay for HEV nucleic acid detection results in 6 (.%) positive samples out of 80 subjects, including . males (69/2%) and .. females (30/8%). Based on the analysis by Fisher exact test, no significant association was observed between HEV and gender of the patients (p value= 0.79) (Table 2). In our study, half of the HIV-1 infected patients were over 30 years of age, while the other half were under 30 years. The mean age for 6 HEV positive patients and 74 HEV negative ones was 40.9 and 35.8 years respectively. There was no significant correlation between age and HEV s RNA positivity (p value= 0.18) (Table 3). By measuring the viral load, we could examine the relationship between HIV viral load and HEV infection. The average HIV viral load in positive and negative HEV patients was 14471.92 and 17016.66 respectively but t-test analysis showed no association between HEV -positive RNA and HIV Viral Load (p value= 0.61) (Table 4). à Discussion: The aim of this study was to evaluate the presence of HEV RNA in blood samples which have been collected from HIV-1-infected patients in Tehran, Iran. In current study we used Real-Time PCR method mainly because it has been shown to be more sensitive and reliable than other methods for identify the infection. Since HEV could be potentially inhibited by anti-retroviral therapy (ART), especially ribavirin (25), none of our HIV-1-infected patients received ribavirin treatment. Thus, our data is not influenced by the viral suppression of antiretroviral therapy. immunosuppressive agents have been shown to facilitate severity or risk of chronicity of hepatitis E infection, HIV infection being one of the possible causes that may lead to HEV persistence (15), and there are Studies of high prevalence of HEV/ HIV co-infection for particular regions (16,17). Moreover, an relationship between exposure to HEV and cirrhosis has been reported in patients with cirrhosis (26), and chronic HEV infection is a leading cause of chronic liver disease in an HIV co-infection patient has been recently described (15). The presence of HEV RNA indicates current infection. This study is the first report to show HEV RNA in HIV-1-infected patients in Tehran, Iran. In this cross-sectional analysis, the overall HEV molecular infection was 7.5% (6/80). The seroprevalence of anti- HEV IgG in HIV-positive cohorts ranges varies from one geographic location to another from 1.5% to 11.2% (19, 20). Incidence of infections caused by HEV, defined by detecting HEV RNA in the serum, is low, ranging from 0 to 1.3% (21-23). In our study, we find HEV-RNA in 6 HIV patients, Unlike studies by Amitis Ramezani et al did not identify any case of HEV-RNA. An explanation for this finding could be the viral suppression observed in HIV-1-infected patients with antiretroviral therapy in their study. our results adapted with results of studies by Madejon et al., (27) Renou et al. (28) and Pischke et al. (29)Therefore, our data also support HEV infection as a viral hepatitis among HIV patients with With relatively moderate prevalence. Hepatitis E virus infection recently has been described as an emerging infection among patients with immunosuppressing conditions of such human immunodeficiency infection (30-32). In current study we found a moderate prevalence (7.5%) of HEV RNA among HIV positive individuals attending the Tehrans hospitals in Iran. Although this rate is higher than the previous studies among Similar patient population in the industrialized countries (33-35), it is lower than the rates of HEV infection reported among some population groups HEV endemic areas of Africa (36) and Asia (15). Carry et al. (39) and Keane et al. (40) have also suggested that the chronic HEV infection may be averted by use of highly active antiretroviral. A sufficiently large sample size is also necessary to establish this finding. The main conclusion of our study is that HEV infection important to consider in the differential diagnosis of otherwise unexplained chronic hepatitis in Iranian HIV-1-infected patients. Furthermore, our study revealed that HEV infection has moderate prevalence in the HIV-infected population of Tehran. Due to the HEV infection that may cause rapidly progressing chronic hepatitis in immunosuppressed HIV co-infection patients, with development of cirrhosis in the short term, Screening for HEV in HIV-infected individuals presenting Symptoms of Hepatitis or with hepatic fibrosis of unknown origin is warranted.
Friday, January 17, 2020
Psychology of Guido Orifice in ââ¬ÅLife Is Beautifulââ¬Â Essay
Guido Orefice, the main character from ââ¬ËLa Vita E Bella,ââ¬â¢ is a very optimistic person. He works for his uncle in a hotel in Italy. He keeps bumping into a lady, whom he considers to be his princess, Principessa Dora. Guido does many things and takes many risks just to see Dora. So they fall in love with each other and get married. They have a boy name Joshua. Their life is very great until the Nazis come and take them all away to a concentration camp. On that very same day it is Joshuaââ¬â¢s 7th birthday. Guido says that he has planned a birthday surprise and that they are going to a fun place to play fun games. Guido tells his son that he needs to be quiet and do what the guards say while the adults go and play games. He also said that every game they win and for every time they do something correctly they get a certain number of points. The first person to win 1,000 points gets a real tank. Joshua really wants it so he does what he is told to. So while Joshua is hiding all the other kids are being gassed and killed. Also Guido is working very hard so he does not get killed and can make his son happy. He gives up his food and other basic needs to have his son think they are playing a game. By the end of the war, Guido says they have 940 points; the Nazis are mercilessly killing the Jews. Guido tell Joshua to hide in a little box, and not to come out until he comes back or until it is totally quiet, and that this will get him to 1,000 points and he will him the game. Guido then dresses up as a girl and goes looking for his wife. A Nazi comes and takes him into an alley and shoots him. Soon the gunshots die down and everyone leaves. Then Joshua comes out of his box and looks around. He sees a large tank coming towards him and is excited because he won the game and got his tank. In the end, Joshua is a grown man and you hear him say, ââ¬Å"This is my story. This was the sacrifice my father made. This was his gift to me.â⬠Erik Erikson identified eight psychosocial stages during which an individualââ¬â¢s primary goal is to satisfy desires associated with inborn social needs. He hypothesized that from infancy through adulthood, we proceeds through these stages, each of which is related to a different problem that needs to be resolved. If the potential problem is dealt withà successfully it will result in a positive personality trait. If not dealt with properly he or she may become anxious, worried, or troubled and develop social and personality problems. Guido has gone through every stage with a successful result. He has trust, autonomy, initiative, industry, identity and intimacy. Generativity versus stagnation is the Stage 7 problem. So far, Guido is leaning towards generativity, but it could change. If Guido had remained alive till Stage 8, he would have integrity instead of despair. Sigmund Freud hypothesized five psychosexual stages during which a childââ¬â¢s primary goal is to satisfy desires associated with innate biological needs. Freud believed that the interactions between parent and child greatly influenced the childââ¬â¢s social development and future social interactions. Guido is currently in the genital stage, the last stage that lasts from puberty through adulthood. It is the time when an individual has renewed sexual desires that he or she seeks to fulfill through relationships. Guido must have had a problem during the oral stage so therefore he had an oral fixation. Guido loves to talk and make people laugh, that is how we figure that out. Lawrence Kohlberg developed a theory to explain moral development. His theory had some similar features to the other analysts. He classified moral reasoning into 3 levels, pre-conventional, conventional, and post-conventional. The three levels are each divided into two stages. Also, he suggested that everyone progresses through the levels in order, from lowest to highest. Not many people make it to the higher stages of moral development. Guido is considered to be in Stage 3 because his wife and his son guide his moral decisions. Guido can understand the actions and talk of Stage 4 where moral reasoning is determined most by confirming laws of society. Abraham Maslow was interested in human motivations, especially in how humans go about choosing which biological or social needs to satisfy. He proposed the hierarchy of needs. It is an ascending order with biological needs at the bottom and social needs at top. This shows that we first satisfy our biological needs before social ones. Before the Nazis came and took Guidoà and his family away, Guido was on the highest level, the level of Self-Actualization. It involves developing and reaching our full potential as a unique human being. When he was in the concentration camp, his whole hierarchy of needs started all over again and he was back at level one. When he was shot he was still at level one because he had no protection and harm. Carl Rogers had a personality theory that was often called the self-theory because of his emphasis on the ââ¬Ëself.ââ¬â¢ Our society also leads us astray with conditions of worth. As we grow up, our parents, teachers, peers, the media, and others, only give us what we need when we show we are ââ¬Å"worthy,â⬠rather than just because we need it. We get a drink when we finish our class, we get something sweet when we finish our vegetables, and most importantly, we get love and affection if and only if we behave. These actions of only getting positive regard on condition are called conditional positive regard. Because we do indeed need positive regard, these conditions are very powerful, and we bend ourselves into a shape determined by a society that may or may not truly have our best interests at heart. A good little boy or girl may not be a healthy or happy boy or girl. Over time, this ââ¬Å"conditioningâ⬠leads us to have conditional positive self-regard as well. We begin to like ourselves only if we meet up with the standards others have applied to us, rather than if we are truly actualizing our potentials. And since these standards were created without keeping each individual in mind, more often than not we find ourselves unable to meet them, and therefore unable to maintain any sense of self-esteem. Guido had unconditional positive regard and unconditional positive self-regard. This is the opposite of what is above. Guido was loved no matter what happened and he loved himself because of that. He did not keep and high goals and was always happy and had a high self-esteem. The last, and probably the most detailed analysis of Guidoââ¬â¢s personality would be Myers-Briggs. According to the Myers-Briggs test, Guido is an ENFP. This stands for Extrovert, Intuitive, Feeling, and Perceiving. ENFPs want to both help and be liked and admired by other people, on an individual and a humanitarian level. They have a large amount of passionate charm. They are outgoing, fun, and genuinely like people. They are warm, affectionate, andà disconcertingly spontaneous. However, their attention span can be short. ENFPs are easily intrigued and distracted by new friends and acquaintances, forgetting about the older ones. ENFPs are pleasant, easygoing, and usually fun to work with. They come up with great ideas, and are a major asset in brainstorming sessions. Follow-through tends to be a problem because they get bored quickly, especially if a newer, more interesting project comes along. They also tend to be procrastinators, both about meeting hard deadlines and about p erforming any small, uninteresting tasks that theyââ¬â¢ve been assigned. Guido meets almost all of the traits of an ENFP.
Thursday, January 9, 2020
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